Hotel Locanda Della Posta, located in the centre of Perugia, offers accommodation in a historical 18th-century building surrounded by shops, restaurants, monuments, and museums, with the Duomo and the National Gallery of Umbria just a short walk away, and convenient public transport connections to the main railway station; the hotel provides friendly staff assistance with tourist information, tours, and reservations, spacious rooms with elegant cherry-wood furnishings and large windows offering city views, free WiFi, buffet-style breakfast served in a frescoed breakfast room or in the guests' room, and a history of famous past residents including Johann Wolfgang von Goethe and Hans Christian Andersen.

Perugia Park Hotel offers spacious guest rooms with free WiFi, an excellent restaurant, a wellness centre with a 25-metre swimming pool, sauna, Turkish bath and gym, and is conveniently located just 500 metres from the small centre of Ponte San Giovanni, 6 km from the centre of Perugia, with each guest room equipped with a flat-screen TV, free WiFi, and en suite bathroom, and also offers a generous buffet breakfast, traditional Umbrian cuisine in the in-house restaurant, a comfortable lounge, 12 modern conference rooms, a bus stop with links to Perugia 300 metres away, Perugia Ponte San Giovanni Train Station 1 km away, Sant'Egidio Airport less than a 10-minute drive away with a free shuttle service available on request.

The modern Hotel La Meridiana offers a large garden with a swimming pool overlooking the Umbrian hills, free parking, soundproofed rooms with air conditioning and free Wi-Fi access, a restaurant serving classic Italian cuisine and Umbrian specialties, a buffet breakfast on the covered patio, sun loungers, satellite TV, digital safes, large modern bathrooms, some rooms with a tea/coffee maker and views of Perugia, and is located 1 km from the Perugia Ferro di Cavallo exit of the Raccordo Autostradale Perugia-A1 motorway, 7.5 km from the historic center of Perugia, and a 10-minute drive from Circolo del Golf Perugia golf club.

Hotel Exe Perusia, located overlooking the Tiber Valley, offers free indoor parking, free Wi-Fi, and a panoramic rooftop terrace with an outdoor pool, while also being reachable by bus from Perugia's historic centre, 1.5 km away; the hotel also includes the Il Canto Sesto restaurant, serving Umbrian cuisine in a 16th-century villa, and offers a breakfast with homemade cakes, yogurt, and fruit, with gluten-free options available upon request, and all air-conditioned rooms at the Perusia provide a TV and private bathroom, with some rooms featuring gemstone-coloured décor and valley views, and the Perugia Train Station is 4.5 km away, with Assisi being a 30-minute drive away.

Best Western Hotel Quattrotorri offers a Special Protection Program, classic-style accommodation with free WiFi and parking, a quiet location outside Perugia city centre, and amenities such as a minibar, satellite TV, and air conditioning, along with a restaurant serving Mediterranean cuisine and sushi, and convenient proximity to the Perugia Golf Club and main motorways for easy access to the city centre.

Relais San Clemente offers a range of leisure facilities, including football pitches, tennis courts, and swimming pools, and is conveniently located just outside Perugia, with horse riding stables and an 18-hole golf course nearby, as well as a games room, poolside bar, piano bar, and restaurant serving fine Umbrian cuisine.

Set on a hill overlooking a green valley, Castello Di Monterone is a historic hotel with an à la carte restaurant, offering a tranquil and relaxing environment both inside and outside the castle walls, with amenities such as a spa, sauna, Turkish bath, swimming pool, and panoramic terrace.

Located 5 km from Perugia, Deco Hotel offers air-conditioned rooms with free Wi-Fi, a balcony, wooden floors, satellite TV, and a private bathroom with a hairdryer and toiletries, some of which have garden views, while guests can enjoy a buffet breakfast in the property's internal bar and relax in the garden veranda, with free on-site parking available and the property being 500 meters from Perugia P.S.G Train Station and 6 km away from Sant'Egidio Airport, with Assisi being 18 km away.

Hotel Giò Jazz Area in Perugia offers free parking and Wi-Fi, a seasonal rooftop pool, sun terrace, gym, spacious rooms with a jazz compilation CD and stereo, some with spa baths or massage chairs, a specialised music shop and music arcade, an auditorium for jazz concerts, a tranquil garden, a restaurant with regional specialities, and is conveniently located near public transportation and the historic centre.

Hotel PentHouse in Perugia offers accommodation with a garden, free private parking, a shared lounge, and a restaurant, featuring air-conditioned rooms with free WiFi, a private bathroom, a desk, a TV with satellite channels, and a safety deposit box, with staff speaking multiple languages and providing practical information on the area at the reception, while guests can enjoy activities such as cycling in and around Perugia, and nearby attractions include Perugia Cathedral, San Severo Church, and Train Station Assisi, with Perugia San Francesco d'Assisi Airport being the nearest airport.