S. Ercolano is a small hotel located opposite the Pincetto stop of Perugia's mini metro, a 5-minute walk from the medieval historic center, offering free nearby parking, views of the Umbrian hills and Assisi, rooms with private bathrooms, and close proximity to Palazzo dei Priori and the 14th-century church it was named after, with Perugia Fontivegge Train Station reachable in 10 minutes by mini metro.

Perugia Park Hotel offers spacious guest rooms with free WiFi, an excellent restaurant, a wellness centre with a 25-metre swimming pool, sauna, Turkish bath and gym, and is conveniently located just 500 metres from the small centre of Ponte San Giovanni, 6 km from the centre of Perugia, with each guest room equipped with a flat-screen TV, free WiFi, and en suite bathroom, and also offers a generous buffet breakfast, traditional Umbrian cuisine in the in-house restaurant, a comfortable lounge, 12 modern conference rooms, a bus stop with links to Perugia 300 metres away, Perugia Ponte San Giovanni Train Station 1 km away, Sant'Egidio Airport less than a 10-minute drive away with a free shuttle service available on request.

The Iris is a 17th-century building located near Perugia's Rocca Paolina fortress and the Sant'Ercolano Church, offering a wide panoramic terrace with views of the old city and the hills, tastefully furnished and large rooms with frescoed ceilings and paintings on the walls, each featuring a private bathroom with shower, and conveniently situated a 2-minute walk from the bus terminus in Piazza Partigiani, providing daily departures to Assisi, Gubbio, and Orvieto.

Best Western Hotel Quattrotorri offers a Special Protection Program, classic-style accommodation with free WiFi and parking, a quiet location outside Perugia city centre, and amenities such as a minibar, satellite TV, and air conditioning, along with a restaurant serving Mediterranean cuisine and sushi, and convenient proximity to the Perugia Golf Club and main motorways for easy access to the city centre.

Hotel Vega Perugia offers a peaceful location in the Umbrian countryside with a free outdoor pool, Wi-Fi throughout, shady gardens, bike rentals, tennis courts, and horse-riding stables nearby, making it easy to explore the surrounding countryside, and with its close proximity to Sant'Egidio Airport and a railway station, as well as good road links, Perugia town centre is only 10 minutes away by car, and parking on site is free.

The 4-star Hotel La Rosetta in Perugia’s historical centre offers free WiFi, simply decorated rooms with wood furniture and works of art, air conditioning and a TV, some with a balcony, and a daily breakfast with a variety of options; it is also conveniently located 400 metres from the city’s cathedral, 300 metres from Umbria National Gallery, and a 20-minute walk from Perugia Station.

Hotel Sacro Cuore, located just 4 km outside Perugia's historic centre, offers stunning views of Mount Subasio and Assisi, with beautiful gardens, a chapel, and library, featuring guest rooms in two buildings, one being a historic villa from 1800, all with classic décor, a TV, and private bathroom, serving a continental buffet breakfast and specialising in Umbrian cuisine at the restaurant, with free parking and a nearby bus stop for connections to Perugia and Assisi.

Hotel il Cigno, located a 10-minute drive from the centre of Perugia, offers classic-style accommodation with a balcony, free Wi-Fi, air-conditioned rooms with a TV, parquet floors and a safe, a private bathroom with a hairdryer and free toiletries, an Italian breakfast served daily, free private parking on site, and is situated a 10-minute drive from Lake Trasimeno, with the A 1 being 55 km away.

Montebello Park Hotel in Perugia offers guests a garden, free private parking, a terrace, and a bar, along with air-conditioned rooms featuring a desk, safety deposit box, flat-screen TV, balcony, and private bathroom with a bidet, as well as mountain views, free WiFi, a concierge service, and luggage storage space, with nearby attractions including Perugia Cathedral, San Severo Church, and Train Station Assisi.

Hotel Astor in Perugia offers a terrace, bar, shared lounge, air-conditioned rooms with free WiFi and private bathrooms, room service, concierge service, desk, TV, balcony in some units, multilingual staff at the 24-hour front desk, and is conveniently located near popular attractions such as Perugia Cathedral, San Severo Church, Perugia Train Station, Corso Vannucci, and Piazza IV Novembre Perugia, with Perugia San Francesco d'Assisi airport just 13 km away and a paid airport shuttle service available.